Dr Thomas Schlitt Dr Thomas Schlitt
Head of Bioinformatics Group

Thomas Schlitt is a in Lecturer Bioinformatics at King's College London Department of Medical and Molecular Genetics and the Centre for Bioinformatics(KCBI)


Educational Background

since December 2006 Lecturer and Groupleader in Bioinformatics at King's College London

12/2003-11/2006: Bioinformatics Research Fellow
01/2000-11/2003: PhD in Bioinformatics at the EBI
1992-1999: Diplom in Biologie University of Giessen

Bioinformatics of Gene Networks

The main aim of our research is to untangle and understand gene networks with a particular focus is on transcription regulatory networks. Various large-scale datasets can be represented as graphs (networks), for yeast this was done e.g. for protein-protein interaction data, transcription factor localisation data or microarray data on deletion mutants. The number of organisms for which such large-scale datasets are available is increasing rapidly. These data sets have to be combined to get a picture of the “real” network in the cell.

We are using such networks to study the gene networks of humans and other organisms in more detail. We use these networks to predict functional relationships between genes. The network approach allows to predict the function of uncharacterised genes and to identify genes involved in disease processes.

To the official group webpage King's College London